PFKL anticorps (AA 669-699)

N° du produit ABIN7876365

L’anticorps anti-PFKL Polyclonal Lapin est utilisé pour la détection de PFKL dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour PFKL anticorps (AA 669-699) (ABIN7876365)

Antigène: PFKL (Phosphofructokinase, Liver (PFKL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PFKL anticorps

Épitope: AA 669-699

Fonction: PFKL Antibody / ATP-PFK / ATP-dependent 6-phosphofructokinase liver type

Immunogène: A portion of amino acids 669-699 from the human protein was used as the immunogen for the PFKL antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the PFKL antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PFKL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PFKL

Antigène: PFKL (Phosphofructokinase, Liver (PFKL))

Autre désignation: PFKL

Sujet: The PFKL protein is an enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a key step in the glycolytic pathway. It also plays a role in regulating glucose metabolism, which is crucial for maintaining healthy blood sugar levels. Dysregulation of the PFKL protein has been linked to metabolic disorders such as diabetes and obesity. While it is primarily found in the liver, where it helps regulate glucose production, it is also found in other tissues such as skeletal muscle and adipose tissue.

UniProt: P17858

Pathways: Negative Regulation of Hormone Secretion, L'effet Warburg