Integrin Alpha2b anticorps (AA 675-714)
Aperçu rapide pour Integrin Alpha2b anticorps (AA 675-714) (ABIN7876394)
Antigène
Voir toutes Integrin Alpha2b (CD41) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 675-714
-
Fonction
- ITGA2B Antibody / Integrin alpha 2b
-
Purification
- Antigen affinity purified
-
Immunogène
- E. coli-derived recombinant human protein (amino acids A675-R714) was used as the immunogen for the ITGA2B antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal dilution of the ITGA2B antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- After reconstitution, the ITGA2B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Integrin Alpha2b (CD41)
-
Autre désignation
- ITGA2B
-
Sujet
- Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. It is mapped to 17q21.32. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
-
UniProt
- P08514
-
Pathways
- Integrin Complex
Antigène
-