Nestin anticorps (AA 698-844)

N° du produit ABIN7876459

Cet anticorps anti-Nestin Monoclonal Souris (Clone NES-2911) (ABIN7876459) détecte spécifiquement Nestin dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Nestin anticorps (AA 698-844) (ABIN7876459)

Antigène: Nestin (NES)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Nestin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: NES-2911

Détail du produit anti-Nestin anticorps

Épitope: AA 698-844

Fonction: Nestin Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 698-844) was used as the immunogen for the Nestin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Nestin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Nestin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Nestin

Antigène: Nestin (NES)

Autre désignation: Nestin

Sujet: Nestin is a major intermediate filament (IF) protein of embryonic central nervous system progenitor cells. It is also a component of the dynamic IF network during muscle development, where it polymerizes with Desmin and Vimentin. Nestin co-assembles with Vimentin or -internexin and forms heterodimer coiled-coil molecules which then further assemble into 10 nml IFs. Deletion of the IF consensus rod domain in nestin alters nestin localization in CNS precursor cells and radial glial cells in vivo. Nestin is a marker for neuroepithelial stem cells, glioma cells and tumor endothelial cells during rapid growth. During axon elongation of differentiation neurons, nestin localizes to the growth cones and may play a role in growth cone guidance. In the rat adrenal gland, nestin is expressed by the zona fasciculata and the zona reticularis. Nestin is also expressed by dermatomal cells and by myoblasts during the earliest stages of myogenesis.

UniProt: P48681