Complement Factor H anticorps (AA 751-780)
Aperçu rapide pour Complement Factor H anticorps (AA 751-780) (ABIN7876733)
Antigène
Voir toutes Complement Factor H (CFH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 751-780
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Fonction
- Complement factor H Antibody / CFH
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 751-780 from the human protein was used as the immunogen for the Complement factor H antibody.
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Isotype
- IgG
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the Complement factor H antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Complement factor H antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Complement Factor H (CFH)
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Autre désignation
- Complement factor H
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Sujet
- This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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UniProt
- P08603
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Pathways
- Système du Complément, Cellular Response to Molecule of Bacterial Origin
Antigène
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