GPBAR1 anticorps (AA 76-310)

N° du produit ABIN7876743

L’anticorps anti-GPBAR1 Polyclonal Lapin est utilisé pour la détection de GPBAR1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour GPBAR1 anticorps (AA 76-310) (ABIN7876743)

Antigène: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPBAR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-GPBAR1 anticorps

Épitope: AA 76-310

Fonction: TGR5 Antibody / GPBAR1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids N76-S310) was used as the immunogen for the TGR5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the TGR5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TGR5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur GPBAR1

Antigène: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Autre désignation: TGR5

Sujet: The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor for bile acids (M-BAR) and TGR5 as is a protein that in humans is encoded by the GPBAR1 gene. This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.

UniProt: Q8TDU6

Pathways: Signalisation WNT, Hormone Transport, Sensory Perception of Sound