IRS2 anticorps (AA 83-1338)

N° du produit ABIN7876932

L’anticorps anti-IRS2 Polyclonal Lapin est utilisé pour la détection de IRS2 dans des échantillons de Humain et Rat. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour IRS2 anticorps (AA 83-1338) (ABIN7876932)

Antigène: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRS2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IRS2 anticorps

Épitope: AA 83-1338

Fonction: Insulin receptor substrate 2 Antibody / IRS2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids R83-E1338) was used as the immunogen for the Insulin receptor substrate 2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Insulin receptor substrate 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Insulin receptor substrate 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur IRS2

Antigène: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Autre désignation: Insulin receptor substrate 2

Sujet: Insulin receptor substrate 2 (IRS2) is a protein that in humans is encoded by the IRS2 gene. It is mapped to 13q34. This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. IRS2 is expressed in many cells, it may be essential for signaling by several receptor systems.

UniProt: Q9Y4H2

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process