Cet anticorps anti-Aurora Kinase B Monoclonal Souris (Clone ARRK2-1) (ABIN7877053) détecte spécifiquement Aurora Kinase B dans IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
Optimal dilution of the AURKB antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
4 °C,-20 °C
Stockage commentaire
Store the AURKB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Antigène
Aurora Kinase B (AURKB)
Autre désignation
AURKB
Sujet
Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]