Aurora Kinase B anticorps (AA 89-251)

N° du produit ABIN7877054

Cet anticorps Souris Monoclonal détecte spécifiquement Aurora Kinase B dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Aurora Kinase B anticorps (AA 89-251) (ABIN7877054)

Antigène: Aurora Kinase B (AURKB)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Aurora Kinase B est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ARRK2-1

Détail du produit anti-Aurora Kinase B anticorps

Épitope: AA 89-251

Fonction: AURKB Antibody / Aurora B

Purification: Protein G affinity

Immunogène: Amino acids 89-251 were used as the immunogen for this AURKB antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the AURKB antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the AURKB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Aurora Kinase B

Antigène: Aurora Kinase B (AURKB)

Autre désignation: AURKB

Sujet: Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]

UniProt: Q96GD4

Pathways: TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades