PIAS2 anticorps (AA 93-311)

N° du produit ABIN7877179

Cet anticorps anti-PIAS2 Polyclonal Lapin (ABIN7877179) détecte spécifiquement PIAS2 dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PIAS2 anticorps (AA 93-311) (ABIN7877179)

Antigène: PIAS2 (Protein Inhibitor of Activated STAT, 2 (PIAS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIAS2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-PIAS2 anticorps

Épitope: AA 93-311

Fonction: PIAS2 Antibody

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids E93-K311) was used as the immunogen for the PIAS2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PIAS2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PIAS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PIAS2

Antigène: PIAS2 (Protein Inhibitor of Activated STAT, 2 (PIAS2))

Autre désignation: PIAS2

Sujet: E3 SUMO-protein ligase PIAS2 is an enzyme that in humans is encoded by the PIAS2 gene. It is mapped to 18q21.1. This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.

UniProt: O75928

Pathways: Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling