ITGA3 anticorps (AA 96-324)

N° du produit ABIN7877250

L’anticorps anti-ITGA3 Polyclonal Lapin est utilisé pour la détection de ITGA3 dans des échantillons de Humain. Il a été validé pour WB, ELISA, FACS, IF et IHC (p).

Aperçu rapide pour ITGA3 anticorps (AA 96-324) (ABIN7877250)

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ITGA3 anticorps

Épitope: AA 96-324

Fonction: Integrin alpha 3 Antibody / ITGA3

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids L96-L324) was used as the immunogen for the Integrin alpha 3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Integrin alpha 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Integrin alpha 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ITGA3

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Autre désignation: Integrin alpha 3

Sujet: ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. It is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. This gene is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the ?3?1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex