Angiotensin I Converting Enzyme 1 anticorps (full length)

N° du produit ABIN7877659

Cet anticorps anti-Angiotensin I Converting Enzyme 1 Monoclonal Souris (Clone ACE-3764) (ABIN7877659) détecte spécifiquement Angiotensin I Converting Enzyme 1 dans ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Angiotensin I Converting Enzyme 1 anticorps (full length) (ABIN7877659)

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Angiotensin I Converting Enzyme 1 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ACE-3764

Détail du produit anti-Angiotensin I Converting Enzyme 1 anticorps

Épitope: full length

Fonction: Angiotensin Converting Enzyme Antibody / ACE

Purification: Protein A/G affinity

Immunogène: Full-length recombinant human protein was used as the immunogen for the Angiotensin Converting Enzyme antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Angiotensin Converting Enzyme antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Angiotensin Converting Enzyme antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Angiotensin I Converting Enzyme 1

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Autre désignation: Angiotensin Converting Enzyme

Sujet: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration