Recombinant Cadherin-16 anticorps (full length)
Aperçu rapide pour Recombinant Cadherin-16 anticorps (full length) (ABIN7877749)
Antigène
Voir toutes Cadherin-16 (CDH16) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- Recombinant Ksp-Cadherin Antibody / Cadherin 16 (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant human full-length CDH16 protein was used as the immunogen for the recombinant Ksp-Cadherin antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the recombinant Ksp-Cadherin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the recombinant Ksp-Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Cadherin-16 (CDH16)
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Autre désignation
- Ksp-Cadherin
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Sujet
- This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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UniProt
- O75309
Antigène
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