Recombinant CD63 anticorps (full length)

N° du produit ABIN7877939

Cet anticorps Lapin Monoclonal détecte spécifiquement CD63 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD63 anticorps (full length) (ABIN7877939)

Antigène: CD63

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD63 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: LAMP3-8799R

Détail du produit anti-CD63 anticorps

Épitope: full length

Fonction: Recombinant CD63 Antibody / LAMP-3

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the recombinant CD63 antibody. Its epitope is different from that of mAb LAMP3/529.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CD63 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant CD63 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CD63

Antigène: CD63

Autre désignation: CD63

Sujet: This mAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of mAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

UniProt: P08962