CD63 anticorps (full length) (CF®488A)

N° du produit ABIN7877944

Cet anticorps anti-CD63 Monoclonal Souris conjugué à CF®488A (Clone MX-49-129-5) (ABIN7877944) détecte spécifiquement CD63 dans FACS et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CD63 anticorps (full length) (CF®488A) (ABIN7877944)

Antigène: CD63

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD63 est conjugé à/à la CF®488A

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: MX-49-129-5

Détail du produit anti-CD63 anticorps (CF®488A)

Épitope: full length

Fonction: CD63 Antibody / LAMP-3

Purification: Protein G affinity chromatography

Immunogène: Full length human CD63 was used as the immunogen for this antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the CD63 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the CD63 antibody at 2-8oC, protected from light.

Détails sur CD63

Antigène: CD63

Autre désignation: CD63

Sujet: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

UniProt: P08962