Cyclin A1 anticorps (full length)

N° du produit ABIN7878057

L’anticorps anti-Cyclin A1 Monoclonal Souris est utilisé pour la détection de Cyclin A1 dans des échantillons de Humain et Xenopus laevis. Il a été validé pour WB.

Aperçu rapide pour Cyclin A1 anticorps (full length) (ABIN7878057)

Antigène: Cyclin A1 (CCNA1)

Reactivité: Humain, Xenopus laevis

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin A1 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Clone: XLA1-3

Détail du produit anti-Cyclin A1 anticorps

Épitope: full length

Fonction: Cyclin A1 Antibody / CCNA1 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Recombinant full-length Xenopus laevis Cyclin A1 protein was used as the immunogen for the Cyclin A1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Cyclin A1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Cyclin A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Cyclin A1

Antigène: Cyclin A1 (CCNA1)

Autre désignation: Cyclin A1

Sujet: The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F, and retinoblastoma protein p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34. The antibody detects Xenopus cyclin A in blots. Cyclin A1 is the embryonic cyclin which is present in Xenopus eggs.

UniProt: P78396

Pathways: Apoptose, Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA