ECD/SGT1 anticorps (full length)

N° du produit ABIN7878151

Cet anticorps anti-ECD/SGT1 Monoclonal Souris (Clone PCRP-ECD-1D10) (ABIN7878151) détecte spécifiquement ECD/SGT1 dans IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ECD/SGT1 anticorps (full length) (ABIN7878151)

Antigène: ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ECD/SGT1 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-ECD-1D10

Détail du produit anti-ECD/SGT1 anticorps

Épitope: full length

Fonction: ECD Antibody / SGT1

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the ECD antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the ECD antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ECD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ECD/SGT1

Antigène: ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))

Autre désignation: ECD

Sujet: Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.

UniProt: O95905

Pathways: Regulation of Carbohydrate Metabolic Process