ELK1 anticorps (full length)

N° du produit ABIN7878167

Cet anticorps Souris Monoclonal détecte spécifiquement ELK1 dans WB et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ELK1 anticorps (full length) (ABIN7878167)

Antigène: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ELK1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: PCRP-ELK1-1D9

Détail du produit anti-ELK1 anticorps

Épitope: full length

Fonction: ELK1 Antibody / ETS Like-1 protein Elk-1

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human ELK1 protein was used as the immunogen for the ELK1 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the ELK1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ELK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ELK1

Antigène: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Autre désignation: ELK1

Sujet: Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1 3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5 element.

UniProt: P19419

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling