FLT3 anticorps (full length)

N° du produit ABIN7878241

Cet anticorps anti-FLT3 Monoclonal Souris (Clone FLT3-2458) (ABIN7878241) détecte spécifiquement FLT3 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FLT3 anticorps (full length) (ABIN7878241)

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLT3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FLT3-2458

Détail du produit anti-FLT3 anticorps

Épitope: full length

Fonction: CD135 Antibody / FLT3

Purification: Protein G affinity chromatography

Immunogène: Recombinant full-length human FLT3 protein was used as the immunogen for the CD135 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the CD135 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD135 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur FLT3

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Autre désignation: CD135

Sujet: Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85 % identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.

UniProt: P36888

Pathways: Signalisation RTK