GTF2H2C anticorps (full length)

N° du produit ABIN7878283

Cet anticorps anti-GTF2H2C Monoclonal Souris (Clone PCRP-GTF2H2C-2C9) (ABIN7878283) détecte spécifiquement GTF2H2C dans WB, IF, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GTF2H2C anticorps (full length) (ABIN7878283)

Antigène: GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GTF2H2C est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: PCRP-GTF2H2C-2C9

Détail du produit anti-GTF2H2C anticorps

Épitope: full length

Fonction: GTF2H2C Antibody

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human GTF2H2C protein was used as the immunogen for the GTF2H2C antibody.

Isotype: IgG2c

Information d'application

Indications d'application: Optimal dilution of the GTF2H2C antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot the GTF2H2C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur GTF2H2C

Antigène: GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))

Autre désignation: GTF2H2C

Sujet: Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.

UniProt: Q6P1K8