IRF9 anticorps (full length)

N° du produit ABIN7878453

L’anticorps anti-IRF9 Monoclonal Souris est utilisé pour la détection de IRF9 dans des échantillons de Humain. Il a été validé pour IF et FACS.

Aperçu rapide pour IRF9 anticorps (full length) (ABIN7878453)

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IRF9 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-IRF9-2F8

Détail du produit anti-IRF9 anticorps

Épitope: full length

Fonction: IRF9 Antibody / Interferon regulatory factor 9

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human IRF9 protein was used as the immunogen for the IRF9 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the IRF9 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the IRF9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur IRF9

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Autre désignation: IRF9

Sujet: Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

UniProt: Q00978

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C