PCGF3 anticorps (full length)

N° du produit ABIN7878826

Cet anticorps anti-PCGF3 Monoclonal Souris (Clone PCRP-PCGF3-1D5) (ABIN7878826) détecte spécifiquement PCGF3 dans IF, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PCGF3 anticorps (full length) (ABIN7878826)

Antigène: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PCGF3 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: PCRP-PCGF3-1D5

Détail du produit anti-PCGF3 anticorps

Épitope: full length

Fonction: PCGF3 Antibody / Polycomb group RING finger protein 3

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the PCGF3 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the PCGF3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PCGF3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PCGF3

Antigène: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Autre désignation: PCGF3

Sujet: Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteinerich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.

UniProt: Q3KNV8

Pathways: Chromatin Binding