LMYC anticorps (full length)

N° du produit ABIN7878881

Cet anticorps Souris Monoclonal détecte spécifiquement LMYC dans WB, ELISA, IF et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour LMYC anticorps (full length) (ABIN7878881)

Antigène: LMYC (MYCL) (Protein L-Myc (MYCL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LMYC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-MYCL-2D5

Détail du produit anti-LMYC anticorps

Épitope: full length

Fonction: L-Myc Antibody / MYCL1

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human MYCL protein was used as the immunogen for the L-Myc antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the L-Myc antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the L-Myc antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur LMYC

Antigène: LMYC (MYCL) (Protein L-Myc (MYCL))

Autre désignation: L-Myc

Sujet: Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas, and the L-Myc gene in human small cell lung carcinomas. c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription.

UniProt: P12524

Pathways: L'effet Warburg