MSK1 anticorps (pSer376)

N° du produit ABIN7879734

L’anticorps anti-MSK1 Monoclonal Lapin est utilisé pour la détection de MSK1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MSK1 anticorps (pSer376) (ABIN7879734)

Antigène: MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MSK1 est non-conjugé

Application: Western Blotting (WB)

Clone: FCF-18

Détail du produit anti-MSK1 anticorps

Épitope: pSer376

Fonction: Phospho-MSK1 Antibody (pS376)

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human MSK1 / RPS6KA5 (surrounding pS376) was used as the immunogen for the phospho-MSK1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the phospho-MSK1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the phospho-MSK1 antibody at -20oC.

Détails sur MSK1

Antigène: MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))

Autre désignation: MSK1

Sujet: Mitogen and stress activated protein kinase 1,' also called RPS6KA5, is a serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. [UniProt]

UniProt: O75582

Pathways: Signalisation MAPK, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades