alpha 2 Macroglobulin anticorps

N° du produit ABIN7879957

Cet anticorps anti-alpha 2 Macroglobulin Monoclonal Lapin (Clone ABAO-1) (ABIN7879957) détecte spécifiquement alpha 2 Macroglobulin dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour alpha 2 Macroglobulin anticorps (ABIN7879957)

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp alpha 2 Macroglobulin est non-conjugé

Application: Western Blotting (WB)

Clone: ABAO-1

Détail du produit anti-alpha 2 Macroglobulin anticorps

Fonction: Alpha-2-macroglobulin Antibody / A2M

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human A2M / Alpha 2 Macroglobulin was used as the immunogen for the Alpha-2-macroglobulin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Alpha-2-macroglobulin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the Alpha-2-macroglobulin antibody at -20oC.

Détails sur alpha 2 Macroglobulin

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Autre désignation: Alpha-2-macroglobulin

Sujet: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [RefSeq]

UniProt: P01023

Pathways: Lipid Metabolism