Cyclin E2 anticorps

N° du produit ABIN7880528

Cet anticorps Lapin Monoclonal détecte spécifiquement Cyclin E2 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Cyclin E2 anticorps (ABIN7880528)

Antigène: Cyclin E2 (CCNE2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin E2 est non-conjugé

Application: Western Blotting (WB)

Clone: EDB-3

Détail du produit anti-Cyclin E2 anticorps

Fonction: CCNE2 Antibody / Cyclin E2

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Cyclin E2 / CCNE2 was used as the immunogen for the CCNE2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CCNE2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the CCNE2 antibody at -20oC.

Détails sur Cyclin E2

Antigène: Cyclin E2 (CCNE2)

Autre désignation: CCNE2

Sujet: G1/S-specific cyclin-E2' belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [RefSeq]

UniProt: O96020

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases