Recombinant Cyclin H anticorps

N° du produit ABIN7880529

L’anticorps anti-Cyclin H Monoclonal Lapin est utilisé pour la détection de Cyclin H dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Recombinant Cyclin H anticorps (ABIN7880529)

Antigène: Cyclin H (CCNH)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin H est non-conjugé

Application: Western Blotting (WB)

Clone: 28C49

Détail du produit anti-Cyclin H anticorps

Fonction: CCNH Antibody / Cyclin H

Purification: Affinity chromatography

Immunogène: A synthetic peptide derived from human Cyclin H/p34 was used as the immunogen for the CCNH antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CCNH antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the CCNH antibody at -20oC.

Détails sur Cyclin H

Antigène: Cyclin H (CCNH)

Autre désignation: CCNH

Sujet: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. [UniProt]

UniProt: P51946

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase