CDK4 anticorps

N° du produit ABIN7880539

Cet anticorps anti-CDK4 Monoclonal Lapin (Clone GIC-3) (ABIN7880539) détecte spécifiquement CDK4 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CDK4 anticorps (ABIN7880539)

Antigène: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK4 est non-conjugé

Application: Western Blotting (WB)

Clone: GIC-3

Détail du produit anti-CDK4 anticorps

Fonction: CDK4 Antibody / Cyclin Dependent Kinase 4

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human CDK4 was used as the immunogen for the CDK4 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CDK4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CDK4 antibody at -20oC.

Détails sur CDK4

Antigène: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Autre désignation: CDK4

Sujet: The protein encoded by the CDK4 gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [RefSeq]

UniProt: P11802

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Regulation of Cell Size