CDKN1C anticorps

N° du produit ABIN7880550

L’anticorps anti-CDKN1C Polyclonal Lapin est utilisé pour la détection de CDKN1C dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CDKN1C anticorps (ABIN7880550)

Antigène: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN1C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDKN1C anticorps

Fonction: CDKN1C Antibody / p57 Kip2

Séquence: AAIKKLSGPL ISDFFAKRKR

Purification: Affinity purified

Immunogène: Amino acids AAIKKLSGPLISDFFAKRKR from the human protein were used as the immunogen for the CDKN1C antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CDKN1C antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CDKN1C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CDKN1C

Antigène: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Autre désignation: CDKN1C

Sujet: Cyclin-dependent kinase inhibitor 1C (p57 Kip2), also known as CDKN1C, is a protein which in humans is encoded by the CDKN1C imprinted gene. It is mapped to 11p15.4. This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

UniProt: P49918

Pathways: Cycle Cellulaire, Dopaminergic Neurogenesis