DKK2 anticorps

N° du produit ABIN7880625

L’anticorps anti-DKK2 Monoclonal Souris est utilisé pour la détection de DKK2 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour DKK2 anticorps (ABIN7880625)

Antigène: DKK2 (Dickkopf 2 Homolog (DKK2))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DKK2 est non-conjugé

Application: Western Blotting (WB)

Clone: 1833CT856-7-20

Détail du produit anti-DKK2 anticorps

Fonction: DKK2 Antibody

Purification: Protein G purified

Immunogène: Recombinant human DKK2 was used as the immunogen for the DKK2 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the DKK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DKK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur DKK2

Antigène: DKK2 (Dickkopf 2 Homolog (DKK2))

Autre désignation: DKK2

Sujet: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). [UniProt]

UniProt: Q9UBU2

Pathways: Signalisation WNT