EIF4E anticorps
Aperçu rapide pour EIF4E anticorps (ABIN7880753)
Antigène
Voir toutes EIF4E AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- EIF4E Antibody
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Purification
- Affinity purified
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Immunogène
- A synthetic peptide specific to human EIF4E was used as the immunogen for the EIF4E antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the EIF4E antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the EIF4E antibody at -20oC.
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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Autre désignation
- EIF4E
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Sujet
- EIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
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UniProt
- P06730
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Pathways
- BCR Signaling
Antigène
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