FGFR3 anticorps

N° du produit ABIN7880792

Cet anticorps Lapin Polyclonal détecte spécifiquement FGFR3 dans WB, IF et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FGFR3 anticorps (ABIN7880792)

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-FGFR3 anticorps

Fonction: Fibroblast Growth Factor Receptor 3 Antibody / FGFR3

Séquence: EGPTLANVSE LELPADPKWE LSRARLTLGK

Purification: Antigen affinity purified

Immunogène: Amino acids EGPTLANVSELELPADPKWELSRARLTLGK from the human protein were used as the immunogen for the Fibroblast Growth Factor Receptor 3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Fibroblast Growth Factor Receptor 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Fibroblast Growth Factor Receptor 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur FGFR3

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Autre désignation: Fibroblast Growth Factor Receptor 3

Sujet: Fibroblast growth factor receptor 3, also known as CD333, is a protein that in humans is encoded by the FGFR3 gene. This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. The FGFR3 gene is mapped to the HD region on chromosome 4p16.3. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.

UniProt: P22607

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding