GADD45B anticorps

N° du produit ABIN7880926

Cet anticorps anti-GADD45B Polyclonal Lapin (ABIN7880926) détecte spécifiquement GADD45B dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GADD45B anticorps (ABIN7880926)

Antigène: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GADD45B anticorps

Fonction: GADD45B Antibody

Séquence: EELLVAAQRQ DRLTVGVYE

Purification: Antigen affinity purified

Immunogène: Amino acids EELLVAAQRQDRLTVGVYE from the human protein were used as the immunogen for the GADD45B antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GADD45B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the GADD45B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur GADD45B

Antigène: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Autre désignation: GADD45B

Sujet: Growth arrest and DNA-damage-inducible, beta, also known as GADD45B, is a protein which in humans is encoded by the GADD45B gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.

UniProt: O75293

Pathways: Cycle Cellulaire