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HLA-ABC anticorps

L’anticorps anti-HLA-ABC Monoclonal Souris est utilisé pour la détection de HLA-ABC dans des échantillons de Humain. Il a été validé pour FACS et IF.
N° du produit ABIN7881087
642,40 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour HLA-ABC anticorps (ABIN7881087)

Antigène

Voir toutes HLA-ABC Anticorps
HLA-ABC

Reactivité

  • 92
  • 28
  • 21
  • 19
  • 17
  • 13
  • 13
  • 13
  • 12
  • 11
  • 7
  • 7
  • 6
  • 6
  • 2
  • 2
  • 1
Humain

Hôte

  • 70
  • 18
  • 4
  • 1
Souris

Clonalité

  • 83
  • 9
Monoclonal

Conjugué

  • 47
  • 7
  • 7
  • 7
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HLA-ABC est non-conjugé

Application

  • 67
  • 19
  • 17
  • 16
  • 15
  • 15
  • 10
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

Classe de qualité

Carrier-free

Clone

Bra-23-9
  • Fonction

    HLA-ABC Antibody (azide and preservative free)

    Purification

    Protein A/G affinity

    Immunogène

    Human REH cells (a pre-B leukaemia cell line) was used as the immunogen for the HLA-ABC antibody.

    Isotype

    IgG2a, kappa
  • Indications d'application

    Optimal dilution of the HLA-ABC antibody should be determined by the researcher.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Agent conservateur

    Azide free

    Stock

    -20 °C

    Stockage commentaire

    Aliquot the HLA-ABC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • Antigène

    HLA-ABC

    Autre désignation

    HLA-ABC

    Sujet

    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Immunoprecipitation of lactoperoxidase radioiodinated cell surface proteins and surface sialoglycoproteins radiolabeled by sodium metaperiodate/tritiated sodium borohydride technique confirmed the structure gp44,p12 (consisting of a 44 kDa glycopeptide linked with a non-glycosylated 12 kDa peptide) typical for MHC class I antigen(s) as a structure recognized by Bra23/9. Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

    UniProt

    P01889

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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