IDE anticorps

N° du produit ABIN7881183

L’anticorps anti-IDE Monoclonal Lapin est utilisé pour la détection de IDE dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour IDE anticorps (ABIN7881183)

Antigène: IDE (Insulin-Degrading Enzyme (IDE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IDE est non-conjugé

Application: Western Blotting (WB)

Clone: AOOB-9

Détail du produit anti-IDE anticorps

Fonction: IDE Antibody / Insulin degrading enzyme

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Insulin-degrading enzyme / IDE was used as the immunogen for the IDE antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the IDE antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the IDE antibody at -20oC.

Détails sur IDE

Antigène: IDE (Insulin-Degrading Enzyme (IDE))

Autre désignation: IDE

Sujet: The IDE gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [RefSeq]

UniProt: P14735

Pathways: SARS-CoV-2 Protein Interactome