Recombinant KRT6A anticorps

N° du produit ABIN7881412

L’anticorps anti-KRT6A Monoclonal Lapin est utilisé pour la détection de KRT6A dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant KRT6A anticorps (ABIN7881412)

Antigène: KRT6A (Keratin 6A (KRT6A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT6A est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT6-8120R

Détail du produit anti-KRT6A anticorps

Fonction: Cytokeratin 6A Antibody

Purification: Protein A/G affinity

Immunogène: A recombinant fragment of human KRT6 protein was used as the immunogen for the Cytokeratin 6A antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the Cytokeratin 6A antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Cytokeratin 6A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur KRT6A

Antigène: KRT6A (Keratin 6A (KRT6A))

Autre désignation: Cytokeratin 6A

Sujet: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

UniProt: P02538