LGR5 anticorps

N° du produit ABIN7881466

L’anticorps anti-LGR5 Monoclonal Lapin est utilisé pour la détection de LGR5 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour LGR5 anticorps (ABIN7881466)

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp LGR5 est non-conjugé

Application: Western Blotting (WB)

Clone: CHF-12

Détail du produit anti-LGR5 anticorps

Fonction: GPR49 Antibody / LGR5

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human GPR49 / LGR5 was used as the immunogen for the GPR49 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GPR49 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the GPR49 antibody at -20oC.

Détails sur LGR5

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Autre désignation: GPR49

Sujet: G-protein coupled receptor 49,' or 'Leucine-rich repeat-containing G-protein coupled receptor 5' is a receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development. [UniProt]

UniProt: O75473

Pathways: Signalisation WNT