MTA2 anticorps

N° du produit ABIN7881622

L’anticorps anti-MTA2 Monoclonal Lapin est utilisé pour la détection de MTA2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MTA2 anticorps (ABIN7881622)

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MTA2 est non-conjugé

Application: Western Blotting (WB)

Clone: ACOE-13

Détail du produit anti-MTA2 anticorps

Fonction: MTA2 Antibody / Metastasis associated 1 family member 2

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human MTA2 was used as the immunogen for the MTA2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MTA2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the MTA2 antibody at -20oC.

Détails sur MTA2

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Autre désignation: MTA2

Sujet: This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [RefSeq]

UniProt: O94776

Pathways: Chromatin Binding