Retinoblastoma Protein (Rb) anticorps

N° du produit ABIN7882157

Cet anticorps anti-Retinoblastoma Protein (Rb) Monoclonal Lapin (Clone BHC-18) (ABIN7882157) détecte spécifiquement Retinoblastoma Protein (Rb) dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Retinoblastoma Protein (Rb) anticorps (ABIN7882157)

Antigène: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé

Application: Western Blotting (WB)

Clone: BHC-18

Détail du produit anti-Retinoblastoma Protein (Rb) anticorps

Fonction: Retinoblastoma Antibody / Rb1

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Retinoblastoma / Rb was used as the immunogen for the Retinoblastoma antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Retinoblastoma antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the Retinoblastoma antibody at -20oC.

Détails sur Retinoblastoma Protein (Rb)

Antigène: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Autre désignation: Retinoblastoma

Sujet: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [RefSeq]

UniProt: P06400

Pathways: Mitotic G1-G1/S Phases