Recombinant RPS6KA3 anticorps

N° du produit ABIN7882175

Cet anticorps anti-RPS6KA3 Monoclonal Lapin (Clone 28R24) (ABIN7882175) détecte spécifiquement RPS6KA3 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant RPS6KA3 anticorps (ABIN7882175)

Antigène: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RPS6KA3 est non-conjugé

Application: Western Blotting (WB)

Clone: 28R24

Détail du produit anti-RPS6KA3 anticorps

Fonction: RSK2 Antibody / RPS6KA3 / Ribosomal protein S6 kinase alpha 3

Purification: Affinity chromatography

Immunogène: A synthetic peptide derived from human RSK2 / RPS6KA3 was used as the immunogen for the RSK2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RSK2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the RSK2 antibody at -20oC.

Détails sur RPS6KA3

Antigène: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Autre désignation: RSK2

Sujet: Ribosomal protein S6 kinase alpha 3 (RPS6KA3, RSK2) is a serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. [UniProt]

UniProt: P51812

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades