Stathmin 1 anticorps

N° du produit ABIN7882366

L’anticorps anti-Stathmin 1 Monoclonal Souris est utilisé pour la détection de Stathmin 1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Stathmin 1 anticorps (ABIN7882366)

Antigène: Stathmin 1 (STMN1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Stathmin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: STMN1-8439

Détail du produit anti-Stathmin 1 anticorps

Fonction: Oncoprotein 18 Antibody / OP18 / Stathmin 1

Purification: Protein A/G affinity

Immunogène: A recombinant fragment of human Stathmin 1 protein was used as the immunogen for the Oncoprotein 18 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Oncoprotein 18 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Oncoprotein 18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Stathmin 1

Antigène: Stathmin 1 (STMN1)

Autre désignation: Oncoprotein 18

Sujet: Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

UniProt: P16949

Pathways: Signalisation MAPK, Dynamique des Microtubules