TEK anticorps

N° du produit ABIN7882433

Cet anticorps anti-TEK Polyclonal Lapin (ABIN7882433) détecte spécifiquement TEK dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TEK anticorps (ABIN7882433)

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TEK anticorps

Fonction: TEK Antibody / TIE2

Séquence: EALMNQHQDP LEVTQDVTRE WAKKVVWK

Purification: Antigen affinity purified

Immunogène: Amino acids EALMNQHQDPLEVTQDVTREWAKKVVWK from the human protein were used as the immunogen for the TEK antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the TEK antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TEK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur TEK

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Autre désignation: TEK

Sujet: TIE2, also known as TEK tyrosine kinase, is mapped to 9p21.2. This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP. HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.

UniProt: Q02763

Pathways: Signalisation RTK, Growth Factor Binding