NOD1 anticorps
Aperçu rapide pour NOD1 anticorps (ABIN7882740)
Antigène
Voir toutes NOD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Monkey NOD1 Antibody / CARD4
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Séquence
- NQTLKHLWLI QNQITAK
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Purification
- Affinity purified
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Immunogène
- Amino acids NQTLKHLWLIQNQITAK were used as the immunogen for the Monkey NOD1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Monkey NOD1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Monkey NOD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
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Autre désignation
- NOD1
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Sujet
- Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. NOD1 is a member of NOD-like receptor protein family and is a close relative of NOD2. NOD1 is mapped to 7p14.3. It recognizes bacterial molecules and stimulates an immune reaction. NOD1 protein contains a caspase recruitment domain (CARD). This gene is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. What wore, it has been shown that NOD1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases.
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UniProt
- Q9Y239
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Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
Antigène
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