STAT4 anticorps (pTyr693) (Cy3)
Aperçu rapide pour STAT4 anticorps (pTyr693) (Cy3) (ABIN746216)
Antigène
Voir toutes STAT4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr693
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Réactivité croisée
- Souris
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Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Stat4 around the phosphorylation site of Tyr693
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Isotype
- IgG
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Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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Autre désignation
- Stat4
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Sujet
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Synonyms: STAT4 Tyr693, STAT4 Y693, p-STAT4 Tyr693, signal transducers and activators of transduction 4, CIS4, HSPC060, SOCS4, SOCS6, SSI4, STAI4, STAT 4, STAT4, STATI4, Suppressor of cytokine signaling 6, STAT4_HUMAN.
Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011].
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ID gène
- 6775
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UniProt
- Q14765
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Pathways
- Signalistation JAK/STAT
Antigène
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