Recombinant SOX2 anticorps

N° du produit ABIN7938504

Cet anticorps anti-SOX2 Monoclonal Lapin (Clone 230225G1) (ABIN7938504) détecte spécifiquement SOX2 dans IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant SOX2 anticorps (ABIN7938504)

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SOX2 est non-conjugé

Application: Immunofluorescence (IF)

Clone: 230225G1

Détail du produit anti-SOX2 anticorps

Fonction: SOX2 antibody (rAb), 100 μg (Clone 230225G1)

Purification: Protein A Chromatography

Immunogène: This antibody was raised against the SOX2 fusion protein.

Isotype: IgG

Information d'application

Indications d'application: IF: 1:150-1:600 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: SOX2

Sujet:

Background_Plain: Sox2 (SRY related HMG BOX gene 2) is a DNA binding transcription factor and a member of the SOX family of proteins. SOX proteins have an HMG box that binds DNA. Sox2 forms a complex with Oct-4 and controls the expression of a number of genes involved in embryonic. Sox2 is critical for early embryogenesis and for embryonic stem cell pluripotency and thus can serve as a stem cell marker. Overexpression of Sox2 (along with Oct-4, KLF4 and c-Myc) can transform mouse fibroblasts into a state resembling embryonic stem cells (ES cells), referred to as Induced Pluripotency. Defects in Sox2 are the cause of microphthalmia syndromic type 3.

Aliases: ANOP3, MCOPS3

Poids moléculaire: 34 kDa

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis