VASP anticorps (pSer239)

N° du produit ABIN746753

L’anticorps Lapin Polyclonal anti-VASP a été validé pour WB et ELISA. Il convient pour détecter VASP dans des échantillons de Souris.

Aperçu rapide pour VASP anticorps (pSer239) (ABIN746753)

Antigène: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VASP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-VASP anticorps

Épitope: pSer239

Specificité: This phosphorylation site is homologous to that of Ser235 in Mouse and Ser236 in Rat.

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human VASP around the phosphorylation site of Ser239

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur VASP

Antigène: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Autre désignation: VASP

Sujet:

Synonyms: Vasodilator-stimulated phosphoprotein, VASP

Background: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.

ID gène: 7408

UniProt: P50552

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation