HTR2C anticorps (AA 372-458) (FITC)

N° du produit ABIN7965082

Cet anticorps Lapin Polyclonal détecte spécifiquement HTR2C dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour HTR2C anticorps (AA 372-458) (FITC) (ABIN7965082)

Antigène: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTR2C est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-HTR2C anticorps (FITC)

Épitope: AA 372-458

Fonction: Anti-5-HT2C Receptor/HTR2C Antibody FITC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human 5-HT2C Receptor/HTR2C recombinant protein (Position: N372-V458).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HTR2C

Antigène: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Autre désignation: HTR2C

Sujet:

Background: This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.

Gene Full Name: 5-hydroxytryptamine receptor 2C

ID gène: 3358

UniProt: P28335

Pathways: Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour