ACTN2 anticorps (AA 567-696) (Fluoro647)

N° du produit ABIN7965713

L’anticorps anti-ACTN2 Polyclonal Lapin est utilisé pour la détection de ACTN2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour ACTN2 anticorps (AA 567-696) (Fluoro647) (ABIN7965713)

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTN2 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-ACTN2 anticorps (Fluoro647)

Épitope: AA 567-696

Fonction: Anti-ACTN2 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ACTN2 recombinant protein (Position: E567-E696).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ACTN2

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Autre désignation: ACTN2

Sujet:

Background: Alpha-actinin 2 is a protein which in humans is encoded by the ACTN2 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: actinin alpha 2

ID gène: 88

UniProt: P35609

Pathways: Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity