Angiopoietin 1 anticorps (Middle Region) (HRP)

N° du produit ABIN7968482

L’anticorps anti-Angiopoietin 1 Polyclonal Lapin est utilisé pour la détection de Angiopoietin 1 dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour Angiopoietin 1 anticorps (Middle Region) (HRP) (ABIN7968482)

Antigène: Angiopoietin 1 (ANGPT1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Angiopoietin 1 anticorps (HRP)

Épitope: Middle Region

Fonction: Anti-Angiopoietin-1/ANGPT1 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by three amino acids,and from the related rat sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Angiopoietin-1, different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: ANGPT1

Sujet:

Background: Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin 1 is mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.

Gene Full Name: angiopoietin 1

ID gène: 284

UniProt: Q15389

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process