Angiopoietin 2 anticorps (C-Term) (Fluoro647)

N° du produit ABIN7968529

Cet anticorps Lapin Polyclonal détecte spécifiquement Angiopoietin 2 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Angiopoietin 2 anticorps (C-Term) (Fluoro647) (ABIN7968529)

Antigène: Angiopoietin 2 (ANGPT2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 2 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-Angiopoietin 2 anticorps (Fluoro647)

Épitope: C-Term

Fonction: Anti-Angiopoietin 2/ANGPT2 Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Angiopoietin 2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Angiopoietin 2

Antigène: Angiopoietin 2 (ANGPT2)

Autre désignation: ANGPT2

Sujet:

Background: Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60 % homologous with Angiopoietin 1. Angiopoietin-2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. Angiopoietin 1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.

Gene Full Name: angiopoietin 2

Sequence Similarities: Contains 1 fibrinogen C-terminal domain.

ID gène: 285

UniProt: O15123

Pathways: Signalisation RTK