ARNT anticorps (AA 416-789)

N° du produit ABIN7970268

Cet anticorps Lapin Polyclonal détecte spécifiquement ARNT dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ARNT anticorps (AA 416-789) (ABIN7970268)

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARNT est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-ARNT anticorps

Épitope: AA 416-789

Fonction: Anti-HIF1 beta/ARNT Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human HIF1 beta shares 86%,83% amino acid (aa) sequences identity with mouse,rat HIF1 beta,respectively.

Attributs du produit: Anti-HIF1 beta/ARNT Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HIF1 beta recombinant protein (Position: V416-E789). Human HIF1 beta shares 86% and 83% amino acid (aa) sequences identity with mouse and rat HIF1 beta, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ARNT

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Autre désignation: ARNT

Sujet:

Background: ARNT is also known as HIF1-beta or HIF1B. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. It is mapped to 1q21.3. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. ARNT is a structural component of the XRE-binding form of the Ah receptor. It also functions in concert with RelB in a CD30-induced negative feedback mechanism.

Gene Full Name: aryl hydrocarbon receptor nuclear translocator

Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.

Poids moléculaire: 87 kDa

ID gène: 405

UniProt: P27540

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg